Print BOIN Decision Boundaries

Display the interval boundaries and the integer decision boundaries produced by boin_boundary.

Usage

# S3 method for class 'boin_boundary'
print(x, cohort_size = NULL, ...)

Arguments

x

An object of class boin_boundary.

cohort_size

Integer scalar or NULL. When supplied, only the sample sizes that are multiples of cohort_size are shown, which is how the boundaries are consulted during a trial with equally sized cohorts.

...

Further arguments, currently ignored.

Value

The object x, invisibly.

Examples

bd <- boin_boundary(target = 0.30, max_n = 18, extrasafe = TRUE)
print(bd, cohort_size = 3)
#> BOIN decision boundaries
#>   target DLT rate : 0.3
#>   p_saf / p_tox   : 0.18 / 0.42
#>   lambda_e        : 0.2365
#>   lambda_d        : 0.3585
#>   cutoff_eli      : 0.95
#>   safety cutoff   : 0.9
#> 
#>                                                  
#> Number of patients treated         3 6 9 12 15 18
#> Escalate if # of DLT <=            0 1 2  2  3  4
#> Deescalate if # of DLT >=          2 3 4  5  6  7
#> Eliminate if # of DLT >=           3 4 5  7  8  9
#> Stop at lowest dose if # of DLT >= 2 4 5  6  7  8