Display the decision table produced by decision_table_3p3:
one row per number of patients and range of DLTs sharing a decision, for
dose escalation and, with mtd_rule = "expand", for the search for
the MTD, followed by what happens once escalation stops.
Usage
# S3 method for class 'decision_table_3p3'
print(x, ...)Details
A data frame that no longer has the columns or attributes of a decision table, for example after selecting columns, is printed as a plain data frame.
Examples
print(decision_table_3p3())
#> 3+3 decision table, MTD rule: previous (the dose below the one declared too toxic)
#>
#> Dose escalation
#> Patients DLTs Decision
#> 3 0 Escalate
#> 3 1 Treat 3 more patients at this dose
#> 3 >= 2 Stop escalation
#> 6 <= 1 Escalate
#> 6 >= 2 Stop escalation
#>
#> Stop escalation means that this dose and all higher doses are too
#> toxic. The MTD is the dose below the one at which escalation stopped,
#> and no MTD is selected when escalation stops at the starting dose. When
#> the highest dose is escalated from, it is the MTD.
print(decision_table_3p3(mtd_rule = "expand"))
#> 3+3 decision table, MTD rule: expand (the highest dose with at most 1 DLT in 6)
#>
#> Dose escalation
#> Patients DLTs Decision
#> 3 0 Escalate
#> 3 1 Treat 3 more patients at this dose
#> 3 >= 2 Stop escalation
#> 6 <= 1 Escalate
#> 6 >= 2 Stop escalation
#>
#> Search for the MTD
#> Patients DLTs Decision
#> 3 0 Treat 3 more patients at this dose
#> 6 <= 1 Select this dose as the MTD
#> 6 >= 2 Move to the next lower dose
#>
#> Stop escalation means that this dose and all higher doses are too
#> toxic. The search for the MTD starts at the dose below the one at which
#> escalation stopped, or at the highest dose when it is escalated from.
#> No MTD is selected when the search moves below the starting dose.