Package index

Two Continuous Endpoints

Functions for clinical trials with two continuous co-primary endpoints

ss2Continuous()

Sample Size Calculation for Two Co-Primary Continuous Endpoints (Approximate)

power2Continuous()

Power Calculation for Two Co-Primary Continuous Endpoints

twoCoprimary2Continuous()

Unified Interface for Two Co-Primary Continuous Endpoints

ss1Continuous()

Sample Size Calculation for a Single Continuous Endpoint

Two Binary Endpoints (Asymptotic Methods)

Functions for clinical trials with two binary co-primary endpoints using asymptotic normal approximation

ss2BinaryApprox()

Sample Size Calculation for Two Co-Primary Binary Endpoints (Asymptotic Approximation)

power2BinaryApprox()

Power Calculation for Two Co-Primary Binary Endpoints (Approximate)

twoCoprimary2BinaryApprox()

Unified Interface for Two Co-Primary Binary Endpoints (Approximate Methods)

ss1BinaryApprox()

Sample Size Calculation for a Single Binary Endpoint

Two Binary Endpoints (Exact Methods)

Functions for clinical trials with two binary co-primary endpoints using exact inference methods

ss2BinaryExact()

Exact Sample Size Calculation for Two Co-Primary Binary Endpoints

power2BinaryExact()

Exact Power Calculation for Two Co-Primary Binary Endpoints

twoCoprimary2BinaryExact()

Unified Interface for Two Co-Primary Binary Endpoints (Exact Methods)

rr1Binary()

Rejection Region for Two-Arm Trials with a Single Binary Endpoint

dbibinom()

Probability Mass Function of Bivariate Binomial Distribution

Mixed Continuous and Binary Endpoints

Functions for clinical trials with one continuous and one binary co-primary endpoint

ss2MixedContinuousBinary()

Sample Size Calculation for Two Co-Primary Endpoints: One Continuous and One Binary

power2MixedContinuousBinary()

Power Calculation for Two Co-Primary Mixed Endpoints

twoCoprimary2MixedContinuousBinary()

Unified Interface for Mixed Continuous and Binary Co-Primary Endpoints

Mixed Count and Continuous Endpoints

Functions for clinical trials with one count (negative binomial) and one continuous co-primary endpoint

ss2MixedCountContinuous()

Sample Size Calculation for Two Co-Primary Endpoints: One Count and One Continuous

power2MixedCountContinuous()

Power Calculation for Two Co-Primary Endpoints (Count and Continuous)

twoCoprimary2MixedCountContinuous()

Unified Interface for Mixed Count and Continuous Co-Primary Endpoints

ss1Count()

Sample Size Calculation for a Single Count Endpoint (Negative Binomial)

Utility Functions

Helper functions for correlation bounds and design comparisons

corrbound2Binary()

Calculate Correlation Bounds Between Two Binary Outcomes

corrbound2MixedCountContinuous()

Calculate Correlation Bounds Between Count and Continuous Outcomes

design_table()

Create Design Comparison Table for Two Co-Primary Endpoints

Visualization and Output

Methods for displaying and visualizing results

print(<twoCoprimary>)

Print Method for twoCoprimary Objects

print(<twoCoprimary_table>)

Print Method for twoCoprimary_table Objects

plot(<twoCoprimary>)

Plot Method for twoCoprimary Objects